In the ever-evolving world of firearms, handgun cartridges come and go. Some rounds carve a permanent place in history due to their performance, reliability, or widespread use. Others, however, quietly fade into the background – overshadowed by more efficient, more popular, or simply better-balanced competitors. Whether they were niche ideas, commercial missteps, or once-popular options now in decline, certain handgun cartridges are clearly on the brink of extinction.
Here are six that, while still in circulation, are rapidly losing relevance and may soon become footnotes in firearm history.
1. .45 GAP – A Solution to a Problem No One Had

The .45 GAP (Glock Auto Pistol) was born from a well-meaning idea: cram .45 ACP performance into a 9mm-sized frame. Glock’s engineers designed it to deliver the power of .45 ACP in a shorter, high-pressure package that would fit into slimmer handguns with smaller grips. The idea looked good on paper, but reality didn’t cooperate.
Despite some brief attention from law enforcement agencies, the cartridge never gained meaningful civilian traction. The truth is, most shooters were already satisfied with .45 ACP or had moved on to more manageable rounds like 9mm. Today, ammo availability is sparse, and few handguns are even chambered for it. The .45 GAP has become little more than a historical curiosity.
2. .32 H&R Magnum – Overshadowed in Its Own Family

The .32 H&R Magnum was supposed to be a significant upgrade over the .22 LR and .22 Magnum for revolvers, and to its credit, it delivered more punch without requiring a big-frame gun. Introduced in 1982, it offered modest recoil and better ballistic performance than its rimfire cousins. However, its reign was short-lived.
The .327 Federal Magnum quickly stole the spotlight, offering vastly more power – up to three times the energy – while still fitting in compact revolvers. Compared to the .327, the .32 H&R just didn’t hold up. Despite being a decent option for light defensive carry, it’s now relegated to niche status, with dwindling interest and shrinking factory support.
3. .41 Magnum – Neither Here Nor There

The .41 Magnum was introduced in the 1960s as a supposed sweet spot between the .357 Magnum and the .44 Magnum. The concept was to deliver more stopping power than the .357 but less recoil than the .44. Unfortunately, the idea came to market without widespread demand, and few people ever asked for that middle ground. Law enforcement didn’t adopt it in any meaningful way, and hunters tended to stick with proven options like the .44 Magnum.
Even enthusiasts of powerful revolvers often found themselves returning to the more versatile and widely supported .357 or going all-in with the .44. Today, the .41 Magnum feels like an orphaned idea – a round with no clear audience in a market full of better-defined choices.
4. .32 ACP – Outclassed by Modern Pocket Pistols

Once a staple of compact handguns, the .32 ACP was widely used throughout Europe and even saw its share of American pocket pistols. Lightweight, soft-shooting, and compact, it seemed like the perfect round for deep concealment. But times have changed.
The .380 ACP now dominates the pocket pistol category, offering significantly better ballistics while maintaining compact size and manageable recoil. The .32 ACP, in comparison, struggles to provide adequate terminal performance for self-defense. While it may still exist in some older or collector-style handguns, most modern shooters have left the .32 ACP behind.
5. .25 Auto – Arguably Less Effective Than a Sharp Stick

If any cartridge deserves the title of most obsolete, the .25 ACP is a prime candidate. Designed in the early 1900s by none other than John Browning, it was intended for vest-pocket pistols – ultra-compact, concealable firearms. But its performance has always been underwhelming.
A 45-grain bullet traveling at 800 feet per second just doesn’t cut it by today’s standards. Even the humble .22 LR outperforms it in most metrics. Tales abound of .25 ACP rounds failing to stop attackers or bouncing off heavy clothing. It’s underpowered, expensive for what it offers, and generally outclassed in every way. There’s just no modern use case where the .25 Auto makes sense anymore.
6. .40 S&W – Once the King, Now Fading Fast

The .40 S&W had its glory days. Developed as a response to perceived underperformance in law enforcement shootings, it became the darling of police departments and federal agencies. It offered more stopping power than 9mm and fit into guns with similar capacity and size. For years, it was the go-to caliber for duty use. But then things shifted.
Advancements in 9mm bullet technology closed the performance gap, while .40 S&W retained its snappy recoil and higher cost. Law enforcement agencies began migrating back to 9mm for its ease of training and lower recoil. Civilians followed suit, and demand for .40 S&W started to drop sharply. While it’s still available and usable, the writing is on the wall. Its days as a top-tier carry round are fading fast.
Changing Needs, Changing Trends

Handgun cartridges often fall victim to shifts in law enforcement priorities, self-defense philosophies, and improvements in ballistic science. What was once seen as essential can quickly become outdated. For example, the 9mm has re-established dominance, not because other calibers failed, but because modern loads now perform far better than they did 20 years ago. That evolution makes certain “middle-ground” options like the .40 S&W and .45 GAP unnecessary.
The Recoil and Training Factor

Another common theme among these declining cartridges is recoil. Higher recoil often demands more training, and more training means more cost. When a cartridge like 9mm offers manageable recoil and effective stopping power, it becomes the more practical option for most shooters. That’s especially true in law enforcement and civilian self-defense circles, where time and budget constraints matter.
When Niche Doesn’t Justify Production

Some rounds were designed for extremely narrow purposes or hypothetical markets that never materialized. The .41 Magnum and .45 GAP were supposed to bridge gaps—pun intended—but never found broad support. Without mass adoption, manufacturers are reluctant to keep producing ammo or firearms, and once that support vanishes, the cartridge starts circling the drain.
Handgun Market Realities

The modern handgun market is more competitive than ever. Shooters expect availability, affordability, and versatility. If a cartridge can’t deliver at least two of those, it won’t last. That’s why rounds like the .25 Auto and .32 H&R Magnum are disappearing – they simply don’t meet modern expectations.
As the firearm world continues to evolve, other cartridges may join this endangered list. The focus is on performance, practicality, and efficiency. That’s not to say these six are bad – they each had their moment. But the reality is clear: unless something changes drastically, they’ll soon be relegated to the realm of collectors, reloaders, and those who appreciate forgotten pieces of firearm history.

Mark grew up in the heart of Texas, where tornadoes and extreme weather were a part of life. His early experiences sparked a fascination with emergency preparedness and homesteading. A father of three, Mark is dedicated to teaching families how to be self-sufficient, with a focus on food storage, DIY projects, and energy independence. His writing empowers everyday people to take small steps toward greater self-reliance without feeling overwhelmed.